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M9480515.TXT
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1994-08-20
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Document 0515
DOCN M9480515
TI Human immunodeficiency virus serostatus and the risk of postextraction
complications.
DT 9410
AU Dodson TB; Perrott DH; Gongloff RK; Kaban LB; Department of Surgery,
Emory University, Atlanta, GA.
SO Int J Oral Maxillofac Surg. 1994 Apr;23(2):100-3. Unique Identifier :
AIDSLINE MED/94308633
AB Despite the increasing prevalence of human immunodeficiency virus (HIV)
disease in the population and the increasing likelihood that
HIV-positive (HIV+) patients may have an extraction, little is known
about the risk of postoperative complications in this group. The goal of
this investigation was to assess the risk of postoperative complications
in HIV+ patients after tooth extraction. The study was designed as a
retrospective cohort study with a sample consisting of 145 males who
underwent tooth extraction. The patients' medical and dental records
were reviewed to identify HIV serostatus, to document the frequency and
type of postoperative complications, and to collect data on potential
confounding variables. Forty-four patients were identified as HIV+. The
postoperative complication rate in HIV+ patients was 20.9% and for
HIV-negative (HIV-) patients 2.9% (relative risk = 7.0, 95% confidence
interval = 2.0-25.0, P = 0.001). Furthermore, as the manifestations of
the symptoms of HIV infection became more severe, the postextraction
complication rate also increased (P = 0.008). The results of this study
suggest that HIV+ patients have an increased risk of postextraction
complications and as the level of HIV disease increases, the risk of
complications also increases. While the findings of this study are
consistent with studies based on case series, prospective cohort studies
are required to confirm the findings.
DE Acquired Immunodeficiency Syndrome Adult Age Factors Alcohol Drinking
Analysis of Variance Antibiotics/THERAPEUTIC USE AIDS-Related Complex
Chi-Square Distribution Cohort Studies Comparative Study Confounding
Factors (Epidemiology) *Dental Care for Chronically Ill Diabetes
Mellitus Female Human *HIV Infections HIV Seronegativity HIV
Seropositivity Logistic Models Male Odds Ratio Retrospective Studies
Risk Factors Severity of Illness Index Smoking Support, Non-U.S.
Gov't Support, U.S. Gov't, P.H.S. Tooth Extraction/*ADVERSE EFFECTS
JOURNAL ARTICLE
SOURCE: National Library of Medicine. NOTICE: This material may be
protected by Copyright Law (Title 17, U.S.Code).